I would like to recommend using bearing buddies. They replace the grease  
caps on the axle and have a grease zert which allows you to inject fresh grease  
to the bearings. This doesn't eliminate the need for occasionally pulling the  
hub assembly apart and cleaning and checking the bearings for wear. As 
bearings  wear, they also need occasional tightening. An ounce of prevention goes a 
long  way with trailer bearings. I also check the tire temperature and feel 
the area  around the bearing hubs at each stop. You look for consistent 
temperatures.  Anything really hot is a problem.
And what were you thinking? Pulling a R22 down I-95 at 2:00 am is asking  for 
a wheel to fail. :)
 
Rummy