Hank,
The fix for this problem is simple. Normally when you apply caulking you  
drag the tip along the object to get a nice bead to set up. In order to get the  
caulk into the affected areas you need to push the tube along the joint while  
laying on some caulking. This forces the caulk into any voids.
This is not a common problem with R22's, but this discussion has popped up  
from time to time.
 
Rummy



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